Medications that Can Stain Teeth (And What You Can Do About It)

Written by Dr. Holly Nadji • Feb 24 • 1 minute read

Did you know that some common medications can lead to stained or discolored teeth? Even if you're brushing and flossing daily, certain prescriptions might be working against your bright smile. Here's what to look out for—and how to protect your teeth.

Medications That May Cause Tooth Staining

Antibiotics – Tetracycline and doxycycline can cause intrinsic (deep) stains, especially when used during childhood while teeth are still developing.
Antihistamines – Some allergy medications, like Benadryl, have been linked to tooth discoloration over time.
Blood Pressure Medications – Calcium channel blockers may contribute to gum overgrowth and darkening of the teeth.
Antipsychotic or Antidepressant Medications – These may reduce saliva production, leading to dry mouth, which can increase plaque buildup and surface stains.
Iron Supplements – Often prescribed for anemia, these can lead to dark stains if not rinsed or brushed away properly.

What You Can Do

Stay Hydrated – Dry mouth makes staining worse. Drink water regularly and ask your dentist about mouthwashes or saliva substitutes.
Brush and Floss – Keeping up with daily oral hygiene helps prevent buildup that can lead to staining.
Whitening Options – Professional cleanings, whitening treatments, and even gentle polishing can help lift stains and refresh your smile.
Talk to Your Dentist – If you’re on a medication that may be staining your teeth, your dentist can recommend personalized solutions.

Worried About Staining? We Can Help.
We offer gentle, effective cosmetic options to keep your smile bright—no matter what’s in your medicine cabinet. Schedule a consultation today. Call (904) 731-1919.

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